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KMID : 1120320150010000031
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Osteoporosis and Sarcopenia
2015 Volume.1 No. 0 p.31 ~ p.31
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Serum Lipid and Thyroid Function Test was Correlated with BMD in Old Aged Women
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Youn Ju-Hyun
Lee Sa-Ra
Yoon Byung-Koo
Choi Hoon
Kang Byung-Moon
Jang Yoon-Suk
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Abstract
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Objective : To investigate serum marker which are correlated with the low bone mineral density (BMD) in old aged (≥65 years) Korean women.
Methods : Medical records of 154 postmenopausal women aged over 65 years who visited health care clinic of our hospital were reviewed retrospectively. We investigated women's baseline characteristics including age, height, weight, body mass index (BMI) and laboratory findings including serum lipid profile, thyroid hormone, calcium, phosphorus, bone alkaline phosphatase. Bone mineral density (BMD) was measured with DXA (Prodigy; GE-lunar, Houston, TX, USA). The correlation between laboratory test result and BMD was analyzed using R statistical package (version 2.13.1).
Results : Mean age was 69.77 ± 6.45 years and mean BMI was 24.46 ± 3.63(kg/m2). The low BMD including osteoporosis and osteopenia was significantly associated with age, Triiodothyronine (T3) and HDL-cholesterol level. The low femur BMD was associated with serum HDL-cholesterol level. The lumbar BMD was significantly correlated with serum-cholesterol, HDL.. T3 was negatively correlated with lumbar and femur BMD and T4 was negatively correlated with femur BMD. TSH was no significant relationship with BMD.
Conclusion : The levels of serum HDL-cholesterol and T3 could be used as indirect markers for low BMD in old aged women.
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KEYWORD
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Bone, Lipid, Old age, Thyroid hormone
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